TY - JOUR AU - Kumar, Prevesh PY - 2022/06/15 Y2 - 2024/03/28 TI - An Overview on Fecal Microbiota Transplantation and it’s Therapeutic Applications on Dysbiosis: As Golden Juice JF - Asian Journal of Pharmaceutics (AJP) JA - AJP VL - 16 IS - 2 SE - REVIEW ARTICLES DO - 10.22377/ajp.v16i2.4380 UR - http://www.asiapharmaceutics.info/index.php/ajp/article/view/4380 SP - AB - <p>In current scenario, the investigational studies in pathology fields focus on those microbiotas which can produce<br>sever disorders and also terminate the microbiota colonies that cause or which altered and arise with some diseasecausing<br>agents. Fecal microbiota transplantation (FMT) may alter the acceptors gut microbiota and maintain the<br>composition in normal range, which helps to give beneficial pharmacological effects in gastrointestinal tract<br>(GIT) related disease as well as, extra-GIT disorders. Alteration in microbiomes have given appropriate clinical<br>perceptions in both gut and oral disorders. FMT re-established miscellaneous bacterial profile to GIT. The study<br>was focused on the evaluation of efficacy of this method to treat various infections arises with Clostridium difficile<br>bacteria. From the various studies, it may be hypothesized that the FMT reflects that it has potency to treat the<br>C. difficile infections and achieved success rate in between 80 and 100%. Fecal microbiota can be transplant by<br>both either antegrade or retrograde routes. The history of FMT belongs to the 4th century and comes in enforcement<br>in 2013 after approving by the USFDA.</p> ER -