Novel method for spectrophotometric analysis of hydrochlorothiazide tablets using niacinamide as hydrotropic solubilizing agent

R K Maheshwari, Ravi Shankar Shukla

Abstract


In the present investigation, 2 M niacinamide (an inexpensive drug) solution was employed as hydrotropic solubilizing agent to solubilize poorly water-soluble drug hydrochlorothiazide for its spectrophotometric analysis. The proposed
method is new, simple, environmentally friendly, accurate, and reproducible. Accuracy, reproducibility, and precision of the
proposed method were validated statistically.


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References


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DOI: http://dx.doi.org/10.22377/ajp.v2i1.178

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