Fast dissolving meloxicam formulation for acute dental pain: Thoughts to ponder

Editor AJP

Abstract


In the April-June issue of Asian Journal of Pharmaceutics
2008, Inamdar et al. have reported the development
of a new formulation of meloxicam based on solid
dispersion technique using a number of polymers.[1] This
eloquently performed work demonstrated that via the
incorporation of optimized solid dispersion attributes
into fast disintegrating tablets it is possible to further
enhance the dissolution profile of meloxciam such that
within 1 min almost 95% of the drug release occurred
under ideal conditions of dissolution

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References


Inamdar N, Bhise K, Memon S. Solubility enhancement and

development of dispersible tablet of meloxicam. Asian J Pharma

;2:128-32.

Jamali F, Aghazadeh-Habashi A. Rapidly dissolving formulations

for quickabsorption during pain episodes: Ibuprofen. Int J Clin

Pharmacol Ther 2008;46:55-63.

Aghazadeh-Habashi A, Jamali F. Pharmacokinetics of meloxicam

administered as regular and fast dissolving formulations to the

rat: Influence of gastrointestinal dysfunction on the relative

bioavailability of two formulations. Eur J Pharm Biopharm

(Epub).




DOI: http://dx.doi.org/10.22377/ajp.v2i4.307

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