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formulations increased dexamethasone flux 200â€“400 fold over the control, but permeability coefficients were decreased by 4 times.The superior transdermal flux of dexamethasone was due to 1000 fold improvement in solubilization of dexamethasone by microemulsions using lecithin. It can be concluded from the study that the dexamethasone microemulsions can be potentially used for improved topical drug delivery.
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