The Photocatalytic and Biological Activity of Cuucumin Coated with Lanthanum￾doped Copper Oxide Nanoparticles

Abstract

Aim: The study focuses on the synthesis and evaluation of curcumin-coated  lanthanum-doped copper oxide
(La-CuO) nanoparticles (NPs), aiming to combine the bioactivity of curcumin with the photocatalytic and
antimicrobial properties of La-CuO. Materials and Methods: Curcumin-coated La-CuO NPs were characterized
using transmission electron microscopy, scanning electron microscopy, Fourier-transform infrared and X-ray
diffraction, providing insights into their morphology, size distribution, functional groups, crystalline structure, and
phase composition. The study explored the photocatalytic effects of these NPs on thiodicarb pesticide residues in
water, revealing that the NPs significantly reduced the pesticides’ half-life when exposed to sunlight. In addition,
curcumin, a compound in turmeric, is noted for its anti-diabetic properties, including blood sugar control,
oxidative stress reduction, and enhanced insulin sensitivity. Results and Discussion: Photocatalysis studies show
increased efficiency and faster reactions, and the DT50 value, or half-life, is important in environmental chemistry.
This study suggests new uses for curcumin-coated La-CuO NPs in environmental remediation and wastewater
treatment. Curcumin-coated La-CuO NP’s antidiabetic effects were evaluated by inhibiting the α-glucosidase
enzyme. Conclusion: According to this study, CuO NPs inhibit diabetes by 40.23%. La-CuO NPs coated with
curcumin have been shown to have promising antidiabetic properties. According to research, turmeric’s polyphenol
curcumin may have insulin-sensitizing properties that aid in blood sugar control. Curcumin has been shown to
improve β-cell function, reduce insulin resistance, and prevent β-cell death, making it a promising treatment for
diabetes.