Formulation of Sun Screen Gel by Incorporating Titanium Dioxide Nanoparticles and Its Evaluation

Abstract

Aims: The aim of sunscreen gel by incorporating active ingredient in the range of nano particle size, i.e., titanium
dioxide is against sun screen and suntan preparations is to assist the skin painful effects and as a good cosmetic for
well-being. Materials and Methods: The combination of ingredients were used, such as titanium dioxide, raspberry
oil, Jojoba oil, carbopal, polyethylene glycol, methyl paraben, glycerin and rose oil, and distilled water. The titanium
dioxide nanoparticles were used as good cosmetic and act against sun screen effect as a sunscreen agent, Jojoba
oil and raspberry oil were also used as sunscreen agents, in the present investigation. Carbopal was used as gelling
agent and poly ethylene glycol as emollient, glycerin for glossy effect and moisturizing agent, methylparaben as
preservative, rose oil as flavoring agent and distilled water used as aqueous phase. The formulations were made
by mixing the mentioned ingredients in different proportions by coding F1 to F6 to conclude the best among the
prepared formulations for further scope of research. The prepared formulation for evaluated for suitable parameters
such as physical appearance/visual inspection, skin irritation, determination of pH, perfume stability, spreadability,
viscosity, and sun protection factor (SPF). Results and Discussion: All the formulations showed a white color
appearance with a pleasant odor and good perfume stability. The pH for F1 to F6 were 6.2, 6.5, 6.4, 6.8, 6.5, and
7.0, and all the formulations do not show any skin irritation and spreadability shows from average to very good. The
viscosity values for F1 were 3101, for F2 were 3216, for F3 were 3315, for F4 were 3418, for F5 were 3400, and
for F6 were 3627. For the SPF, an in vitro method is performed using the Mansur equation, and the obtained grade
of SPF is high-to-very high protection. Conclusion: After performing all the necessary evaluation tests to decide
the best formulation among the prepared, the F6 formulation was selected as best formulation.