Acyclovir-loaded chitosan nanoparticles
Main Article Content
Abstract
I read the recent publication by Rajendran et al.
on acyclovir-loaded chitosan nanoparticles with a
great interest. It is concluded that “acyclovir-loaded
chitosan nanoparticle suspension appears to be
promising enough for effective management of
ocular viral infections.†I agree that the mentioned
nanoparticle can be an effective pharmaceutical
technique. However, whether this new preparation is
actually effective in actual clinical situation requires
further pharmacokinetic assessment and real clinical
trial. Finally, it should be noted that the improved
penetration of drug in such preparation is mainly
observed in high chitosan content form.
on acyclovir-loaded chitosan nanoparticles with a
great interest. It is concluded that “acyclovir-loaded
chitosan nanoparticle suspension appears to be
promising enough for effective management of
ocular viral infections.†I agree that the mentioned
nanoparticle can be an effective pharmaceutical
technique. However, whether this new preparation is
actually effective in actual clinical situation requires
further pharmacokinetic assessment and real clinical
trial. Finally, it should be noted that the improved
penetration of drug in such preparation is mainly
observed in high chitosan content form.
Downloads
Download data is not yet available.
Article Details
How to Cite
Wiwanitkit, V. (2014). Acyclovir-loaded chitosan nanoparticles. Asian Journal of Pharmaceutics (AJP), 5(2). https://doi.org/10.22377/ajp.v5i2.96
Section
Articles
This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.
References
Rajendran NN, Natrajan R, Kumar RS, Selvaraj S. Acyclovir-
loaded chitosan nanoparticles for ocular delivery. Asian J Pharm
;4:220-6.
Hasanovic A, Zehl M, Reznicek G, Valenta C. Chitosan-
tripolyphosphate nanoparticles as a possible skin drug delivery
system for aciclovir with enhanced stability. J Pharm Pharmacol
;61:1609-16.